Ultraviolet radiation and melanoma

with a special focus on assessing the risks of stratospheric ozone depletion

Publisher: U.S. Environmental Protection Agency, Office of Air and Radiation in Washington, D.C

Written in English
Published: Downloads: 91
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  • Melanoma -- Epidemiology,
  • Ozone layer depletion -- Health aspects,
  • Ultraviolet radiation -- Health aspects,
  • Tumors, Radiation-induced -- Epidemiology

Edition Notes

Statementproject director, John S. Hoffman ; project manager and principal editor, Janice D. Longstreth.
ContributionsHoffman, John S. 1950-, Longstreth, Janice D., United States. Environmental Protection Agency. Office of Air and Radiation.
LC ClassificationsRA645.M45 U48 1987
The Physical Object
Paginationv. <4 > :
ID Numbers
Open LibraryOL2149430M
LC Control Number88602151

capacity against ultraviolet radiation relative to eumelanin, and has been shown to amplify ultraviolet-A-induced reactive oxygen species3–lobservations,however,complicatetheassumption that melanoma risk is completely ultraviolet-radiation-dependent. For example, unlike non-melanoma skin cancers, melanoma is not. @article{osti_, title = {Speculations on the role of ultraviolet radiation in the development of malignant melanoma}, author = {Kripke, M.L.}, abstractNote = {Interest in the etiology of human malignant melanoma has increased considerably in recent years. The basis for this heightened concern can be attributed to two seemingly unrelated issues. @article{osti_, title = {Quantifying lifetime exposure to ultraviolet radiation in the epidemiology of cutaneous malignant melanoma: A pilot study}, author = {Lea, C S and Selvin, S and Buffler, P A and Scotto, J and Berwick, M}, abstractNote = {This pilot study uses a unique method to calculate cumulative lifetime exposure to, ultraviolet radiation-b to determine if this refined method. On the basis of a large body of evidence from human and experimental studies, the monograph concludes that solar radiation is carcino-genic to humans, causing cutaneous malignant melanoma and nonmelanocytic skin cancer. Evidence for the carcinogenicity of ultraviolet A, B, and C radiation was judged sufficient in experimental animals.

Ultraviolet (UV) rays are an invisible form of radiation. They can pass through your skin and damage your skin cells. Sunburns are a sign of skin damage. Suntans aren't healthy, either. They appear after the sun's rays have already killed some cells and damaged others. UV rays can cause skin damage during any season or at any temperature. Health Effects of Exposure to Low Levels of Ionizing Radiation: BEIR V, by National Research Council Board on Radiation Effects Research (page images at NAP) Filed under: Radiation -- Measurement Optical Radiation Measurements: The NBS Scale of Spectral Irradiance (Washington: GPO, ), by Robert D. Saunders and J. B. Shumaker (page. Melanoma is a potentially life-threatening skin cancer of the melanocytes, the cells that make melanin (brown pigment). Melanoma’s fatality rate is higher than that of basal cell and squamous cell cancers; it accounts for more than 80 percent of all skin-cancer deaths. Early detection and treatment greatly increase the likelihood of cure. Ultraviolet (UV) Radiation What is UV radiation? Radiation is the emission (sending out) of energy from any source. Ultraviolet (UV) radiation is a form of electromagnetic radiation. The main source of UV radiation (rays) is the sun, although it can also come from man-made sources such as tanning beds and welding torches. Radiation exists across [ ].

Melanoma incidence is directly related to age, with highest rates in individuals over the age of 55 years, making it a clear age-related disease. In this review, we will focus on UV-induced carcinogenesis and photo aging along with natural protective mechanisms that reduce amount of “realized” solar radiation dose and UV-induced by: UV radiation is a proven cause of basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), which often appear on sun-exposed areas of ately, when discovered early enough, these common forms of skin cancer are almost always curable. UV exposure that leads to sunburn has proven to play a strong role in developing melanoma, the most dangerous of the three most common types of . In contrast to the well-established association between ultraviolet radiation (UVR) exposure and skin cancers, the relationship between UVR and uveal malignant melanoma (UM) remains controversial. To address this controversy, we evaluated the incidence rates of cutaneous malignancies in the eyelids as a proxy for UVR exposure in the ocular region using a population-based cancer : Ezekiel Weis, Sebastian Q. Vrouwe, David B. LeBaron, Matthew B. Parliament, Jerry A Shields, Carol L. Skin cancers, predominantly basal-cell and squamous-cell carcinomas, have accounted for an estimated 40 percent of all cancers in the United States in recent years, and their frequency has been Cited by:

Ultraviolet radiation and melanoma Download PDF EPUB FB2

Marisa Klein-Gitelman, Jerome Charles Lane, in Textbook of Pediatric Rheumatology (Seventh Edition), Ultraviolet Radiation. Ultraviolet radiation (UV), in particular UVB, is a well-known trigger of cutaneous as well as systemic lupus.

UVB produces a variety of inflammatory responses: It directly induces keratinocytes to release chemokines and cytokines, which recruit memory T cells and.

Wallingford SC, Iannacone MR, Youlden DR, et al. Comparison of melanoma incidence and trends among youth under 25 years in Australia and England, Int J Cancer. ; – World Health Organization. Solar Ultraviolet Radiation: Global Burden of Disease from solar ultraviolet radiation.

Map. Ultraviolet radiation lies between wavelengths of about nanometres (1 nanometre [nm] is 10 −9 metre) on the visible-light side and about 10 nm on the X-ray side, though some authorities extend the short-wavelength limit to 4 nm.

In physics, ultraviolet radiation is traditionally divided into four regions: near (– nm), Ultraviolet radiation and melanoma book (– nm), far (– nm), and extreme (below. Ultraviolet (UV) radiation is a form of electromagnetic radiation that comes from the sun and man-made sources like tanning beds and welding torches.

Radiation is the emission (sending out) of energy from any source. There are many types of radiation, ranging from very high-energy (high-frequency) radiation – like x-rays and gamma rays – to.

Studies have shown that exposure to ultraviolet (UV) radiation from the sun increases your risk of getting melanoma, especially if you had sunburns during childhood.

Over the last several years, a team of scientists has used genetically engineered mice to confirm the link between UV and melanoma. Ultraviolet Radiation and Malignant Melanoma Article Literature Review in Advances in Experimental Medicine and Biology February with 19 Reads How we measure 'reads'.

The ultraviolet radiation from tanning beds increases the risk of melanoma. The International Agency for Research on Cancer finds that tanning beds are "carcinogenic to humans" and that people who begin using tanning devices before the age of thirty years are 75% more likely to develop : Ultraviolet light (Sun, tanning devices).

Essential features of the epidemiology and photobiology of cutaneous malignant melanoma (CMM) in Norway were studied in comparison with data from countries at lower latitudes. Arguments for and against a relationship between ultraviolet radiation (UV) from sun and sun beds are by: Melanoma is a particularly aggressive type of skin cancer, and its incidence has been increasing steadily since the s.

This article will review the extensive epidemiologic data demonstrating that ultraviolet radiation (UVR) exposure, from the sun or artificial tanning beds, is the most important environmental risk factor for melanoma; the Cited by: It has been estimated that solar ultraviolet radiation accounts for approximately 93 percent of skin cancers and about half of lip cancers.

This translates to approximately Ultraviolet radiation and melanoma book, life-threatening cancers (cutaneous malignant melanoma) per year in Canada, as well as 65, less serious cancers (basal cell cancer, squamous cell cancer and lip.

Ultraviolet (UV) is electromagnetic radiation with wavelength from 10 nm (with a corresponding frequency of approximately 30 PHz) to nm ( THz), shorter than that of visible light but longer than radiation is present in sunlight, and constitutes about 10% of the total electromagnetic radiation output from the is also produced by electric arcs and specialized lights, such.

In addition, this melanoma-promoting effect of ultraviolet radiation is accentuated further by its ability to induce tolerance against cutaneous tumor antigens, unmasked, for example, by UV-induced cell damage. Although the immunosuppressive properties of ultraviolet radiation are most pronounced with UVB, UVA also has such properties (Halliday Cited by: 2.

Exposure to ultraviolet (UV) radiation has been implicated in melanoma formation. Glenn Merlino and colleagues now show, in a mouse model, that UVB irradiation induces the recruitment of. CHAPTER ULTRAVIOLET RADIATION AND SKIN CANCER Skin cancer is the most commonly occurring cancer in the United States, affecting some one million Americans and accounting for about 2% of all cancer deaths.

The most serious form of skin cancer, melanoma, is expected to be diag-nosed in Marylanders in Melanoma, while only. Solar Ultraviolet Radiation Global burden of disease from solar ultraviolet radiation Robyn Lucas Tony McMichael Wayne Smith Bruce Armstrong Editors Annette Prüss-Üstün, Hajo Zeeb, Colin Mathers, Michael Repacholi World Health Organization Public Health and the Environment Geneva Skin specialists recommend that people use sunscreens that protect the skin from ultraviolet radiation.

In medicine, ultraviolet B radiation also comes from special lamps or a laser and is used to treat certain skin conditions such as psoriasis, vitiligo, and skin tumors of cutaneous T.

Ultraviolet radiation Sunlight is a continuous spectrum of electromagnetic radia-tion that is divided into three major spectrums of wave-length: ultraviolet, visible and infrared The UV range is the most significant spectrum of sunlight that causes photo-aging and Cited by: Ultraviolet (UV) radiation is the carcinogenic factor in sunlight; damage to skin cells from repeated exposure can lead to the development of cancer.

Ultraviolet (UV) radiation is a form of non-ionizing radiation that is emitted by the sun and artificial sources, such as tanning beds. The beneficial effects of UV radiation include the production of a vital nutrient, vitamin D; however, overexposure may present risks.

Sunburn, premature aging, and skin cancer are all risks to overexposure. Ultraviolet radiation plays a role in the development of age-related macular degeneration and skin cancer. We can take precautions to avoid over exposure to the sun s rays and protect our eyes and skin.

Keywords: sun protection, ultraviolet radiation, macular degeneration, cataracts, skin cancer, elderly, seniors, older adults, aging, Created Date. Get this from a library. Ultraviolet radiation and melanoma: with a special focus on assessing the risks of stratospheric ozone depletion.

[John S Hoffman; Janice D Longstreth; United States. Environmental Protection Agency. Office of Air and Radiation.;].

Ultraviolet radiation and melanoma: with a special focus on assessing the risks of stratospheric ozone depletion / (Washington, D.C.: U.S. Environmental Protection Agency, Office of Air and Radiation, []), by Janice D. Longstreth, John S. Hoffman, and United States. Environmental Protection Agency.

Sunburn is the result of overexposure to the sun's ultraviolet radiation. Long-term cumulative sun exposure increases the risk of melanoma and non-melanoma skin cancer.

Melanoma is a kind of skin cancer, sometimes called malignant melanoma. It arises. PREFACE. THE Author of this very practical treatise on Scotch Loch - Fishing desires clearly that it may be of use to all who had it.

He does not pretend to have written anything new, but to have attempted to put what he has to say in as readable a form as possible. Everything in the way of the history and habits of fish has been studiously avoided, and technicalities have been used as.

Fun in the sun ruins our skin. In New Zealand, most melanomas are related in some way to ultraviolet radiation (UVR).UVR comes from the sun or from man-made sources such as sunbeds and tanning salons.

UVR on the earth's surface is composed of short. Cutaneous malignant melanoma (CMM) rates have been increasing in the United States at an average rate of about 4% per year.

Init was estimated that there would be 25, cases and 5, deaths from CMM in the United States. The exact cause of the increase is unknown, but there is evidence to suggest that increasing exposure to the ultraviolet B (UVB) radiation present in sunlight Cited by: Melanin has a role in absorbing ultraviolet radiation, is an antioxidant and scavenges free radicals.

More continuous sun exposure increases melanin production and epidermal thickness and thus may confer protection against melanoma through photoadaptation.".

This book provides a detailed review of the field of skin cancer and UV radiation and is an excerpt of the International Congress on Skin Cancer and UV Radiation held in Bochum/Germany in October Internationally reknown scientists who have been working in this field for decades have contributed to this book and give a profound insight 5/5(1).

Ultraviolet radiation and melanoma-with a special focus on assessing the risks of stratospheric ozone depletion. Vol. 4, Appendix A of Assessing the risk of trace gases that can modify the stratosphere.

Washington, D.C.: U.S. Environmental Protection Agency. It can, in rare occasion, develop in the intestine or eyes. While the exact cause is not clear, exposure to sunlight or tanning beds which include ultraviolet radiation increases your risk for developing melanoma.

Early detection is important as melanoma can be treated successfully when diagnosed before it 5/5(29). Get this from a library! Ultraviolet radiation and melanoma: with a special focus on assessing the risks of stratospheric ozone depletion.

[Volume IV, Appendix A, Assessing the risks of stratospheric ozone depletion]. [John S Hoffman; Janice D Longstreth; United States. Environmental Protection Agency. Office of Air and Radiation.; American Academy of Dermatology.;].Summary: An IARC Working Group has assessed the available evidence relating to possible detrimental health effects of exposure to artificial ultraviolet radiation through use of indoor tanning facilities, in particular whether their use increases the risk for skin cancer.

What is ultraviolet radiation?. Ultraviolet radiation (UVR) forms part of the electromagnetic spectrum — the energy emitted from the is categorised according to wavelength, which ranges from – nm. UVR is involved in tanning, accelerated skin ageing, ocular damage, and the development of skin cancer.

UVR also has beneficial effects due to the production of vitamin D in the.